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| − | + | Wild-type simulations can be performed using Flux-Balance Analysis (FBA), where a Linear Programming problem is defined by the maximization of one flux of the model, usually the biomass formation, or Parsimonious Flux-Balance Analysis (pFBA) where the same principle applies, but the objective function is the minimization of the sum of the fluxes.<br> | |
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Revision as of 18:54, 29 November 2012
How to do a wild type simulation
OptFlux allows the user to perform a simulation of the "wild-type" strain, i.e. of the model with no genetic modifications.
Access the "Wild Type" option either through the "Simulation" menu or right clicking on the model icon in the clipboard.
Wild-type simulations can be performed using Flux-Balance Analysis (FBA), where a Linear Programming problem is defined by the maximization of one flux of the model, usually the biomass formation, or Parsimonious Flux-Balance Analysis (pFBA) where the same principle applies, but the objective function is the minimization of the sum of the fluxes.