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| − | You can access the " | + | You can access the "Calculate Critical Genes/Reactions" option under the "Model Simplification" menu or by right clicking on the Metabolic Model icon on the clipboard.<br> |
| − | + | <div style="display: block; text-align: left;">http://sites.google.com/site/optfluxhowtos/howtos/model-simplification/performing-structural-simplification/CalculateCriticalMenu.png</div> | |
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In the options you can select the | In the options you can select the | ||
| − | model/project to work, and set up the process.<br>< | + | model/project to work, and set up the process.<br> |
| − | + | <div style="display: block; text-align: left;">http://sites.google.com/site/optfluxhowtos/howtos/model-simplification/performing-structural-simplification/CalculateCriticalOperation.png</div> | |
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If you have created environmental conditions you can select them to be used as constraints in the critical genes/reactions calculation. This means that in this case you will calculate essential genes/reactions in a given environment.<br> | If you have created environmental conditions you can select them to be used as constraints in the critical genes/reactions calculation. This means that in this case you will calculate essential genes/reactions in a given environment.<br> | ||
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| − | And that's all !! Now you can press OK and check the results in the clipboard.<br>< | + | And that's all !! Now you can press OK and check the results in the clipboard.<br> |
| − | + | <div style="display: block; text-align: left;">http://sites.google.com/site/optfluxhowtos/howtos/model-simplification/performing-structural-simplification/CalculateCriticalSolution.png</div> | |
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